Jussi Virtanen has successfully defended his PhD dissertation on the subject of detecting rhinosinusitis with differential mobility spectrometry! Congratulations Jussi! His work consisted of four original peer-reviewed publications on the subject. Our team has been following his work closely, and the IonVision device was featured in two of the publications as the used DMS device.
The first work in the dissertation was on the subject of in vitro detection of the common bacteria causing acute rhinosinusitis with DMS. You can find the article here.
The second publication built on top of the first. The work was a pilot on detecting bacteria from maxillary sinus secretion taken from patients with acute rhinosinusitis. This work is available to read here.
The third work took another step towards noninvasive analysis of rhinosinusitis. In this work, DMS was used to differentiate aspirated nasal air from room air. Focus was also on developing the sampling method suitable for noninvasive nasal air sampling. The test participants in this study were healthy volunteers. You can read this publication here.
The last publication was on the subject of identifying chronic rhinosinusitis from aspirated nasal air based on DMS. The work found suggestions for a distinct VOC profile associated with CRSsNP (chronic rhinosinusitis without nasal polyps). The work is available here.
The full dissertation is available on the Tampere University library site here. The work is in English!
Article header photo credit: Jonne Renvall / Tampereen yliopisto